NOTI-GENÉTICA: Constantes en los genes EGFR y KRA

NOTI-GENETICS: Constants in the EGFR gene and KRA

A recently published study (S. Sakata-2022) made in a japanese population, using a panel of next-generation sequencing (NGS), we examined > 300 adenocarcinomas of the lung, identified in approximately half of the cases, variants constants in the genes EGFR and KRAS, which provides useful information to study and identify variants in these genes in patients with lung adenocarcinomas.

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Investigación en CCT100

Research in CCT100

This year, Cancer Center Tec100, formally began the research department. The activities that took place were different and with a lot of involvement of the network of specialists.

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NOTI-GENÉTICA: Mutaciones deletéreas.

NOTI-GENETICS: deleterious Mutations.

Before deleterious mutations, the cell has an efficient repair system through the pathway Repair by Homologous Recombination (HRR), which allows you to repair mutations of the double-stranded, by activating a complex molecular mechanism that includes a team of genes, within which are found mainly BRCA1/2, ATM, PALB2, and RAD51; however, when there is a mutation in any of the genes of this pathway, is set to a Deficiency in the Homologous Recombination (HRD).

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NOTI-GENÉTICA: Oncología de precisión

NOTI-GENETICS-Oncology precision

The chronic inflammation caused by bacterial and viral infections is strongly related to the etiology and the development of cancer, not only because of the inflammation caused by the infection, but by the integration of sequences of DNA and RNA in human cells.

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